(Also known as Bacopa monniera, Brahmi, Water hyssop)
‘In adults, B monnieri has been reported to be effective in reducing anxiety, thereby allowing improved brain functioning in terms of memory enhancement and elevated mental performance. Concentration and immediate memory span were both significantly improved. On-the-job mental fatigue, measured as total work output, and errors committed per unit time, also were statistically improved.’
Bacopa monnieri. Global information hub on integrated medicine; 2018. Internationally recognised government monograph.
‘BM [BacoMind®] exerts its effects on cholinergic, dopaminergic, and serotonergic pathways by affecting at least five different molecular targets of memory. The memory enhancing effects of BM can be linked to its cumulative effects on these enzyme and receptor based targets.’
Elucidation of molecular mechanism(s) of cognition enhancing activity of Bacomind® : A standardized extract of Bacopa monnieri. Pharmacognosy Magazine; 2016.
‘Study findings suggested that BacoMind® improved the cognitive functions such as attention and verbal memory in elderly individuals and was also found to be well tolerated.’
Efficacy and Tolerability of BacoMind® on Memory Improvement in Elderly Participants – A Double Blind Placebo Controlled Study. J Pharmacology and Toxicology; 2008.
‘These findings suggest that B. monnieri may improve higher order cognitive processes that are critically dependent on the input of information from our environment such as learning and memory.’
The chronic effects of an extract of Bacopa monnieri (Brahmi) on cognitive function in healthy human subjects.; J Psychopharmacology, 2001.
‘The Bacopa monnieri product signiﬁcantly improved performance on the ‘Working Memory’ factor, more speciﬁcally spatial working memory accuracy. The number of false-positives recorded in the Rapid visual information processing task was also reduced for the Bacopa monnieri group following the treatment period. The current study provides support for the two other published studies reporting cognitive enhancing effects in healthy humans after a 90-day administration of the Bacopa monnieri extract.’
Examining the Nootropic Effects of a special extract of Bacopa monniera on Human Cognitive Functioning: 90 day Double-Blind PlaceboControlled Randomized Trial. https://www.ncbi.nlm.nih.gov/pubmed/18683852; 2008.
‘Current evidence suggests BM acts via the following mechanisms – anti-oxidant neuroprotection (via redox and enzyme induction), acetylcholinesterase inhibition and/or choline acetyltransferase activation, β-amyloid reduction, increased cerebral blood flow, and neurotransmitter modulation.’
Neuropharmacological Review of the Nootropic Herb Bacopa monnieri.; Rejuvenation Research; 2013.